Urban European hedgehogs may look harmless, but they can play an important role in the circulation of zoonotic pathogens in cities. In our recent study of 129 hedgehogs from northwestern Italy, we detected several tick- and flea-borne bacteria of public health concern, including Anaplasma phagocytophilum, Borrelia burgdorferi sensu lato (Lyme disease group), Borrelia miyamotoi, and Rickettsia spp., with a Rickettsia closely related to R. asembonensis reported for the first time in this species. These pathogens were found far more frequently in the skin than in internal organs, highlighting the skin as a key interface for vector-borne transmission and a valuable target for surveillance. Our findings, recently published in Veterinary Sciences, underline the importance of considering urban wildlife like hedgehogs in disease monitoring and One Health strategies, especially as human–wildlife interactions continue to increase.